Lack of Influence of SMAD7 Gene rs2337107 Polymorphism on the Risk of Colorectal Cancer in an Iranian Population
نویسنده
چکیده
Colorectal cancer (CRC) as the third most common cancer brings about the fourth cause of worldwide cancer mortality (Jemal et al., 2011; Shemirani et al., 2011). According on World Health Organization (WHO) reports, CRC is one of the common diseases in an Asian population (Moghimi-Dehkordi et al., 2012; Haerian et al., 2014). It is noticeable that incidence of this cancer has been rising in an Iranian population during recent decades (Azadeh et al., 2007; Milanizadeh et al., 2013). Thereby, the importance of CRC as a major worldwide health issue is also increasing in our population (Haghighi et al., 2009). Although numerous risk factors and causes have been taken into account for CRC, genetic component has a great contribution on CRC development. To emphasize this fact, nearly 35% of total cases have been reflected by twinand family based studies (Lichtenstein et al., 2000).
منابع مشابه
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Polymorphism of SMAD7 gene (rs2337104) and risk of colorectal cancer in an Iranian population: a case-control study
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تاریخ انتشار 2014